ACT Research Symposium 2025
12th ACT Research Symposium
"Vascular contributions to cognitive impairment and dementia with a focus on sex differences"
Virtual conference, held via Teams
May 13-14, 2025
The Adult Changes in Thought (ACT) study began in 1994 and has actively shared data with external collaborators to advance innovative projects in aging research. We are excited to host the 12th ACT Symposium to bring together researchers and other interested individuals in person to discuss research related to ACT and brain aging science.
Thank you to all who presented abstracts and proposals!
Did you miss the Symposium or would you like to hear one of the talks again?
Speaker slides and recordings are available below.
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Tuesday, May 13th: Symposium Day 1 |
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Speaker(s) |
Topic |
Presentation |
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Keynote: Modifying risk for dementia: Identifying potential targets for prevention and treatment over the life course |
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ZinniaTV: A non-pharmaceutical tool to support dementia caregiving |
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Associations of Accelerometer Measures of Physical Activity and Sedentary Behavior with Alzheimer’s Disease Related Dementias and Vascular Dementias Classified Using Medicare Claims Data Among Older Black, Hispanic and White Women: The Objective Physical Activity and Cardiovascular Health Study |
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ACT Project 1: Historical cognitive and physical function as predictors of the 24-hour activity cycle |
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The interplay of multi-ancestry polygenic risk scores with vascular and menopause-related factors in Alzheimer's disease and cognitive decline |
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Multi-modal imaging of small vessel disease |
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Vascular Biomarkers and Cognitive Decline in Alzheimer’s Disease Risk |
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Alzheimer’s Disease and Related Dementia Neuropathologies and Exposure to Air Pollution Mixtures in the Adult Changes in Thought Study |
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Some dirt might hurt: why the environment merits attention as a contributor to dementia risk |
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Life Course Core Survey – descriptives of key variables |
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Wednesday, May 14th: Symposium Day 2 |
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Speaker(s) |
Topic |
Presentation |
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Microglial morphology and gene expression are altered in individuals resilient to Alzheimer’s disease |
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Sex and APOE genotype influence microglial gene expression and composition of microglial states in Alzheimer’s disease |
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3D Reconstruction and Segmentation of Dissection Photographs for MRI-Free “Neuropathometry" |
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Early Life Exposures and Cognitive Functioning in Later Life: Findings, and A Case for More and Better Data |
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Proposal: The role of social connection in VCID |
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ACT Project 3: Are your medications increasing your dementia risk? Pharmacoepidemiology and stem cell model evidence on antihypertensives and anticholinergics on dementia prognosis |
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ACT Project 2: Cognitively Defined Subgroups of Alzheimer’s Disease (AD) Dementia |
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