Adult Changes in Thought Study

Historical Life Course & Social Determinants of Health Data

Historical Life Data.png Data Description

The ACT Study administers a one-time survey to participants focused on early life-course environmental exposures, as well as enhanced use of geocoded and U.S. Census-linked data.

Study Forms

  • Life Course Survey - The Life Course Core developed this survey to focus on early life exposures and other life course factors. It is completed once by each current ACT participant starting during the U19 funding period. 

Key Publications

The following publications provide additional detail on the life course data elements. These may be helpful supporting citations when publishing analyses using these data.

  • Tom SE, Hubbard RA, Crane PK, Haneuse SJ, Bowen J, McCormick WC, McCurry S, Larson EB. (2015). Characterization of dementia and Alzheimer's disease in an older population: updated incidence and life expectancy with and without dementia. American Journal of Public Health, 105(2), 408-13.
  • Tom SE, Phadke M, Hubbard RA, Crane PK, Stern Y, Larson EB. (2020). Association of Association of Demographic and Early-Life Socioeconomic Factors by Birth Cohort With Dementia Incidence Among US Adults Born Between 1893 and 1949. JAMA Network Open, 3(7), e2011094.
  • Power MC, Murphy AE, Gianattasio KZ, Zhang YI, Walker RL, Crane PK, Larson EB, Gibbons LE, Kumar RG, Dams-O'Connor K. (2021). Association of Military Employment With Late-Life Cognitive Decline and Dementia: A Population-Based Prospective Cohort Study. Military Medicine, usab413. Advance online publication.