Adult Changes in Thought Study

Adult Changes in Thought Study

Three decades, thousands of patients, one long-term goal: to understand brain aging

Advancing our understanding of cognition, aging, and better ways to delay and prevent Alzheimer’s disease and related dementias

Over the last 3 decades, the Adult Changes in Thought (ACT) study has enrolled and followed several thousand older adults who receive care as Kaiser Permanente Washington members, creating unique and comprehensive longitudinal data sets that can support a wide array of research on factors that affect brain aging.  

ACT is a classic cohort study embedded in a large integrated health care delivery system. Supported by a grant from the National Institute on Aging, our rigorous, population-based clinical and epidemiologic research combine under 3 projects and 6 cores, with extensive forays into basic biologic science and technology research. 

We are proud of our long tradition of research on the vitally important topic of cognition and the aging brain, and we invite you to learn more about our team, how we’re organized, and how to partner with us.