Adult Changes in Thought Study

Coverage of the ACT Study 

Findings from the Adult Changes in Thought (ACT) Study are shared primarily in peer-reviewed medical journals and at professional conferences related to Alzheimer’s disease, geriatrics, and neuroscience. Plain language summaries for study participants are often included in our quarterly participant newsletters as well. 

A list of key publications is provided on our Data Resources page. You can also access a list of all ACT-related papers through the National Library of Medicine’s PubMed ↗ site.

The following news release provides additional context and insights about the scope of the ACT Study and grant award.

Recent News

EYE_ACT_2col.jpgAlzheimer’s vision study improved with home testing

July 16, 2024

The research builds on the ongoing Adult Changes in Thought (ACT) Study, started in 1994. Read more here.



ACT 11th Research Symposium featured in KPWHRI news 
June 11, 2024

The Symposium featured talks related to the theme, "Alzheimer’s Disease and Dementia Biomarkers: Current Advances, Future Directions, Implications for Research". Read more here


ACT 10th Research Symposium featured in KPWHRI news ACT symp 2023 pix1.png
June 16, 2023

The ACT Research Symposium returns with an in-person scientific forum. Read more here



Using long-term data to understand a vulnerable population
May 10, 2023

Studies using data from ACT offer insights into the lives of older adults with dementia who lack family. Read more here


Linda McEvoy.jpgThe ACT Study welcomes Dr. Linda McEvoy!
April 26, 2023

Dr. Linda McEvoy joins the ACT study and KPWHRI as a Senior Investigator. Read more about Dr. McEvoy here. 



Brain Donations: a Gift for Future Generations brains.png
April 26, 2023

One donated brain can make a huge impact, potentially providing information for hundreds of research studies. Read more from the National Institutes of Health here


seattle times 041923.pngTracking King County seniors (and their brains) for clues to dementia and Alzheimer’s
April 14, 2023

Article in the Seattle Times features the ACT Study. See the full story here



eRADAR-story_2col.jpgDementia risk screening tool shows promise in health care setting
August 1, 2022

Study finds that a new tool to help discover undiagnosed dementia, initially developed and validated using ACT data, performed well in 2 separate health systems. See the full story here


New open data to help understand Alzheimer’s
July 29, 2022

Collaborators at the Allen Institute have just released some of the first publicly available data, much of which comes from brain tissue donations from ACT participants, that provides new insights to brain changes in Alzheimer’s disease. See the full story here


ACT-Study_website-homepage_2col.jpgHealthy aging: New tool for research and collaboration
May 12, 2022

Adult Changes in Thought (ACT) Study launches a new website to advance our understanding of brain aging. See the full story here


ACT-Study-cataracts_2col.jpgCataract surgery linked with lessened dementia risk
December 6, 2021

ACT Study researchers, led by Dr. Cecilia Lee at the University of Washington, found patients who had cataract surgery had a 30% lower risk of developing dementia in this recent study published in JAMA Internal Medicine. See the full story here.


Dementia-stories_2col.jpgRoundup of 3 recent studies on dementia risk
November 16, 2021

ACT researchers explore links between hearing loss, military service, and cognitive decline — and look at timeliness of diagnosis. See the full story here.


ACT-PM2.5_story-map_2col.jpgAir pollution linked to higher risk of dementia
August 4, 2021

With data from the ACT Study, researchers associated increased levels of fine particle pollution with a greater risk of dementia. See the full story here.


ACT-Study-NIA-grant_Dementia_2col.jpgGrant of over $55M to boost Alzheimer’s, dementia study
May 20, 2021

Kaiser Permanente Washington will co-lead an expanded ACT Program to better understand the aging brain. See the full story here.


ATN-brain-scan_2col.jpgStudy evaluates biomarker criteria for Alzheimer’s risk
April 27, 2021

One-third of people classified as “highest risk” may not develop Alzheimer’s disease, study suggests. See the full story here.


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Please visit the Kaiser Permanente Washington Health Research Institute’s careers page to view open positions.