Adult Changes in Thought Study

News & Results

Findings from the Adult Changes in Thought (ACT) Study are shared primarily in peer-reviewed medical journals and at professional conferences related to Alzheimer’s disease, geriatrics, and neuroscience. Plain language summaries for study participants are often included in our quarterly participant newsletters as well. 

A list of key publications is provided on our Data Resources page. You can also access a list of all ACT-related papers through the National Library of Medicine’s PubMed ↗ site.

Our recent news release provides additional context and insights about the scope of the ACT Study and grant award.

Recent News

eRADAR-story_2col.jpgDementia risk screening tool shows promise in health care setting
August 1, 2022

Study finds that a new tool to help discover undiagnosed dementia, initially developed and validated using ACT data, performed well in 2 separate health systems. See the full story here


New open data to help understand Alzheimer’s
July 29, 2022

Collaborators at the Allen Institute have just released some of the first publicly available data, much of which comes from brain tissue donations from ACT participants, that provides new insights to brain changes in Alzheimer’s disease. See the full story here


ACT-Study_website-homepage_2col.jpgHealthy aging: New tool for research and collaboration
May 12, 2022

Adult Changes in Thought (ACT) Study launches a new website to advance our understanding of brain aging. See the full story here


ACT-Study-cataracts_2col.jpgCataract surgery linked with lessened dementia risk
December 6, 2021

ACT Study researchers, led by Dr. Cecilia Lee at the University of Washington, found patients who had cataract surgery had a 30% lower risk of developing dementia in this recent study published in JAMA Internal Medicine. See the full story here.


Dementia-stories_2col.jpgRoundup of 3 recent studies on dementia risk
November 16, 2021

ACT researchers explore links between hearing loss, military service, and cognitive decline — and look at timeliness of diagnosis. See the full story here.


ACT-PM2.5_story-map_2col.jpgAir pollution linked to higher risk of dementia
August 4, 2021

With data from the ACT Study, researchers associated increased levels of fine particle pollution with a greater risk of dementia. See the full story here.


ACT-Study-NIA-grant_Dementia_2col.jpgGrant of over $55M to boost Alzheimer’s, dementia study
May 20, 2021

Kaiser Permanente Washington will co-lead an expanded ACT Program to better understand the aging brain. See the full story here.


ATN-brain-scan_2col.jpgStudy evaluates biomarker criteria for Alzheimer’s risk
April 27, 2021

One-third of people classified as “highest risk” may not develop Alzheimer’s disease, study suggests. See the full story here.


We're Hiring

The growth of the ACT Study means we have new openings for scientific researchers as well as for technical positions and project managers. We’re featuring 2 terrific career opportunities for an Associate/Senior Investigator and a Senior Research Associate. Please visit the Kaiser Permanente Washington Health Research Institute’s careers page to view these and other positions.

The Associate/Senior Investigator recruitment is part of the institute’s succession planning and includes taking a visible leadership role within the ACT Study and also leading a well-established and successful aging research program.

The Senior Research Associate will provide strategic scientific leadership and administrative direction for ACT’s research and data infrastructure and collaborate on research in geriatrics and aging.

Join us for the 2022 ACT Symposium.
Coming soon!